Multi-Joint Osteoarthritis Linked to Faster Frailty Decline

A study of over 1,000 Canadian adults found that those with osteoarthritis in two or more joints had higher baseline frailty and progressed to frailty about 40-47% faster over six years compared to those without or with single-joint OA, even after adjusting for physical activity. The findings suggest OA should be viewed as a systemic condition affecting aging trajectories.