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Health · Drug development · published 2026-08-26 · via Endpoints News

Spyre halts RA program for anti-TL1A candidate after Phase 2 disappointment

Spyre Therapeutics is deprioritizing its anti-TL1A antibody for rheumatoid arthritis after the drug failed to meet the company's threshold for success in a mid-stage trial. The decision casts doubt on the broader potential of the candidate, though the company has not disclosed full results.

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Spyre Therapeutics has decided to deprioritize its anti-TL1A antibody program for rheumatoid arthritis after the candidate failed to meet the company's internal success threshold in a Phase 2 trial. The company has not yet disclosed full trial results

Expanded detail and Context are AI-generated analysis; the linked article remains the authoritative source.
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This summary is Al-enhanced to contain extended analysis and broader social context. The original is {NAME); the linked article is the authoritative source. Original headline: “Spyre drops rheumatoid arthritis hopes for anti-TL1A drug after modest Phase 2 data.” Browse more stories.