New Fall 2026 Vaccine Recommendations: RSV for Pregnant, mRNA Flu Shot for Older Adults
ACOG now advises a single dose of the maternal RSV vaccine (Abrysvo) for pregnant individuals from September 1 through March 1. For the first time, an mRNA-based flu vaccine is available for adults aged 50 and older. Adults 65 and older should receive an enhanced flu vaccine when available.
The American College of Obstetricians and Gynecologists has updated its guidance to recommend a single dose of the maternal RSV vaccine Abrysvo for pregnant individuals, with the dosing window running from September 1 through March 1. This timing aligns with typical respiratory virus season patterns.
In a notable development for influenza prevention, an mRNA-based flu vaccine is now available for the first time for adults aged 50 and older. Additionally, adults aged 65 and above are advised to receive an enhanced flu vaccine when it is available, reflecting a tiered approach to respiratory protection this fall.
These recommendations could reshape how vulnerable populations approach fall vaccination. Pregnant individuals may gain better protection for newborns against RSV, while older adults could benefit from newer vaccine technologies that may offer improved efficacy. The expanded availability of mRNA flu vaccines for those 50 and older may increase uptake among a demographic that has historically shown vaccine hesitancy, potentially reducing seasonal hospitalizations and easing strain on healthcare systems during peak respiratory illness months.