49ers defensive tackle Collins suffers season-ending patellar tendon tear

San Francisco 49ers defensive tackle Alfred Collins tore his patellar tendon during Tuesday's practice and will miss the entire 2026 season. The second-year player was expected to start alongside Osa Odighizuwa in Friday's game against the Rams. His injury adds to the team's mounting defensive-line losses, including Mykel Williams, Sam Okuayinonu, and Mikail Kamara.
Collins suffered the injury during a team drill on Tuesday, just before live contact began, according to coach Kyle Shanahan. The 24-year-old had been working back from offseason shoulder surgery, which limited his participation in organized team activities and training camp. His previous highlight came in a 2025 overtime victory over the Rams, where his goal-line strip secured the win.
With Collins sidelined, the 49ers will likely elevate CJ West to a starting role alongside Osa Odighizuwa for Friday's matchup. Rookie Gracen Halton is expected to see increased snaps. James Thompson Jr. could also contribute if he recovers from a hamstring strain, while practice-squad members Kevin Givens and Sebastian Valdez provide additional emergency depth.
The loss of Collins could further strain the 49ers' defensive front, potentially affecting their competitive balance in the NFC West and altering playoff projections. For fans, this may diminish excitement for the upcoming Rams game, as a promising young player's season ends prematurely. The team's mounting injuries could also influence league-wide discussions about practice safety and roster management, as clubs grapple with how to maintain depth amid a grueling season.