Tulane Opens as 18.5-Point Favorite Over Southern Miss

Tulane is an 18.5-point favorite for Saturday's home game against Southern Miss, according to DraftKings. Both teams enter with 1-2 records, with Tulane coming off a loss at Kansas State. The Green Wave will look to rebound at Yulman Stadium.
Tulane's ground game ignited in week two when Jaylin Lucas topped 200 rushing yards, a first in Yulman Stadium's history. However, the Green Wave's opener against Duke was marred by 15 accepted penalties. Kicker Cooper Helmke provided a highlight at Kansas State, converting a 58-yard field goal that set a new program standard.
Southern Miss is in transition under first-year coach Blake Anderson and quarterback Ethan Hampton. After a lopsided win over Alcorn State, the Golden Eagles were routed by Auburn and UConn, with Hampton exiting the latter contest injured. Saturday's 6 p.m. CT matchup marks the conference opener for both squads.
This game could influence early-season momentum for both programs, potentially shaping bowl eligibility and coaching confidence. For Tulane, a convincing win may restore fan enthusiasm and validate their status as a conference contender. For Southern Miss, a competitive showing could provide a morale boost despite the large spread. Bettors and local businesses may also feel economic effects, as the point spread drives wagering activity and game-day attendance in the New Orleans area.