FDA Approves Atebrioz for FOP Patients Aged 12 and Older

Mirum Pharmaceuticals and Incyte said the U.S. FDA has approved Atebrioz (zilurgisertib) tablets. The drug is intended to reduce the total volume of new heterotopic ossification in adults and children aged 12 and older with fibrodysplasia ossans progressiva.
Mirum Pharmaceuticals and Incyte said the FDA has cleared Atebrioz (zilurgisertib) tablets for use in the United States. The approval covers adults and pediatric patients aged 12 and older who have fibrodysplasia ossificans progressiva.
The drug's intended effect is to lower the amount of newly developing heterotopic ossification. Mirum is based in Foster City, California, while Incyte is based in Wilmington, Delaware; both companies are publicly traded on Nasdaq.
For people with FOP and their families, this approval may offer a new option aimed at slowing new abnormal bone formation, potentially reducing disease burden and need for care. Clinicians could gain another tool for patients aged 12 and older. Access, affordability, and long-term outcomes may shape real-world impact, and broader awareness of this rare condition could grow.