Scientists at Dongguk University developed a gene switch that responds to electromagnetic fields, allowing noninvasive and reversible control of gene expression. The switch uses the Lgr4 gene promoter and was demonstrate…
#Biology & genetics
Recent developments in biology and genetics reveal advances across environmental health, disease mechanisms, and evolutionary processes. Research confirms that early-life nutrition shapes lifelong health outcomes, while environmental toxins trigger autoimmune responses through protein modifications rather than genetic changes. Studies of infectious diseases show concerning patterns: mpox remains endemic despite vaccination efforts, and antimalarial drugs persist in mosquitoes long enough to potentially influence parasite development. Conservation biology achieved a notable success with the black robin's recovery from near-extinction, while genomic analysis unveiled how medieval migration reshaped coastal populations' ancestry. Additionally, discoveries about cellular proteins—from E-cadherin's waste-clearing role to SIRPα's involvement in cancer metastasis—illuminate fundamental biological mechanisms underlying disease progression and tissue maintenance.
Researchers at McGill University found that T cells can detect the stiffness of surrounding tissues, and this mechanical signal influences whether they become long-lived memory cells. The discovery challenges the long-he…
A study combining high-resolution mapping and field surveys found that rainforests in the Greater Blue Mountains World Heritage Area are three to four times larger than official maps show. These fire-sensitive ecosystems…
University of California, Riverside researchers observed that two common ant baits alter Argentine ant behavior before killing them. Thiamethoxam eliminated all workers within about seven days, while boric acid killed ro…
A University of Georgia study found that centipedegrass, a common turfgrass in the Southeast, serves as a food source for bees. Researchers collected over 150 foraging bees from 28 species and observed them gathering gra…
A TikTok video of a tiny fish emerging from a borewell prompted an international team to investigate, leading to the discovery of a new genus and species, Gangaichthys indonepalicus. It is the first subterranean fish rec…
Researchers at Hebrew University analyzed feline corneal sequestra, dark necrotic lesions on the eye, using sensitive elemental analysis. They found iron and bromine levels that clearly distinguished affected tissue from…
A study of nearly half a million Dutch blood donors found that haemoglobin and ferritin levels fluctuate both daily and seasonally, peaking in December and bottoming out between June and August. These variations, though …
Australian authorities have not confirmed any human H5N1 infections this year, but standard flu tests cannot distinguish bird flu from seasonal strains, so mild cases could go unnoticed. The current H5N1 substrain has ca…
A series of studies led by UMCG cardiologists found that low-dose digoxin, a centuries-old drug costing pennies a day, was associated with a 25% reduction in heart failure hospitalizations. The research, presented at the…
Researchers reconstructed the evolutionary history of the flightless beetle Carabus blaptoides across Japan's largest island using genetic data from 170 individuals at 70 sites. The beetles exhibit a trade-off between sl…
Researchers used CRISPR-Cas9 to introduce a single extra DNA building block into the Can f 1 gene in dog skin cells, disrupting its function. The edited cells were used to create cloned embryos, resulting in two female b…
A Murdoch University study found that the introduced pathogen Phytophthora dieback degrades grasstree habitats, leading to reduced foraging and digging activity in quendas (Isoodon fusciventer) in Western Australia's jar…
Researchers at Utrecht University developed a genome-wide screening platform that tests how disrupting each human gene affects editing outcomes in cells. They found that knocking out either GJB2 or BET1L increased gene e…
Bacteriophages, viruses that infect bacteria, may offer a solution to antibiotic-resistant infections. Researchers are using artificial intelligence to analyze how these viruses operate. This approach could reveal natura…
A dairy cow miscarriage wastes the resources invested in its pregnancy, including feed, land, water, and the associated greenhouse gas emissions, while also forfeiting future milk production and income. Improving animal …
Canine sarcoptic mange, caused by microscopic mites, is a contagious and zoonotic skin disease that can lead to severe complications if untreated. A new study suggests that topical application of clove oil offers a faste…
A long-standing theory that a unique genetic system drove the evolution of social colonies in ants, bees, and wasps is challenged by a new large-scale analysis. The study suggests genetics alone cannot account for this d…
A widely used food preservative is emerging as a potential factor in rising UK suicide deaths, especially among younger people and men. Researchers suspect the scale of impact may be underestimated and call for restricti…
When dietary fiber is scarce, gut microbes can turn to proteins in the mucus lining for sustenance. Fiber appears to suppress this behavior, while indigestible plant proteins encourage production of beneficial compounds.…
Analysis of U.S. health data from 1999 onward shows blood bicarbonate levels increased by about 7%, while calcium and phosphorus decreased. These shifts correlate with rising atmospheric carbon dioxide. The findings sugg…
The UK's repeated heat waves this summer have made heat stress a leading cause of weather-related sick leave among workers. High temperatures can trigger symptoms ranging from heat rash and cramps to severe exhaustion an…
Cats yowl to communicate a range of needs, from hunger and attention to distress or mating calls. Interpreting the sound requires observing the cat's body language and environmental context. The article explains the beha…
Recent research shows that cells use membrane-less condensates, formed by phase separation, to organize biochemical reactions. This condensate physics provides general principles for how cells respond chemically, complem…
A new study reports that wildfires have destroyed more than 4 million hectares of protected tropical forest since 2001, an area equivalent to twice the size of Wales. The loss highlights the growing threat of wildfires t…
Gabriel Hamer, a Texas A&M AgriLife Research entomologist, conducted a three-month Fulbright trip to Argentina to study Chagas disease vectors. His work aims to improve understanding of the disease's transmission, which …
A new study reveals the evolutionary reasons why birds, the closest living relatives of crocodiles, developed flight while crocodiles did not. Both groups share a common ancestor from about 250 million years ago, but key…
Almost three-quarters of England is now in drought conditions, leading to widespread water use restrictions and severe wildfires. The drought is impacting farming, wildlife, and trees across the region. The duration of t…
Extreme summer drought across Europe has caused widespread grass yellowing, particularly in Britain, as water is diverted to homes and farms. The dry conditions have exposed ancient underground walls and ditches as green…
The Australian National Insect Collection at CSIRO holds 2,000 drawers of butterfly specimens, some collected over a hundred years ago. These historical samples provide a valuable record for studying the effects of clima…
Researchers have identified specific mutation hotspots that allow bacteriophages to rapidly adapt and outcompete antibiotic-resistant bacteria in the human gut. This discovery could inform new strategies to combat drug-r…
The molecular structure of a vaccine influences how the immune system prepares for future pathogen exposure. Researchers are modifying vaccine structures to promote longer-lasting immune responses, particularly for HIV. …
Feral cats and foxes have spread across nearly all of Australia, causing extinctions of many native species. While safe havens have helped protect some mammals, other animal groups remain vulnerable. The study highlights…
Researchers at Pontificia Universidad Católica del Ecuador have officially described a new frog species, Pristimantis milpe, which had been confused with another species for over 100 years. The discovery relied on re-exa…
A long-term study in Chicago examined tree cover changes over 11 years. Neighborhoods that lost mature tree canopy experienced higher death rates, particularly in the city's hottest areas. The findings suggest preserving…
A Bournemouth University study found that ospreys that prefer to nest away from others of their species, called 'pioneering pairs,' are key to faster population recovery. These birds help expand the species' range and ar…
New GPS tracking research provides clear evidence that invasive barred owls are a major threat to northern spotted owls in California's old-growth forests. The study also shows that managing barred owl populations can he…
Scientists have pinpointed specific genes that act as roadblocks for lipid nanoparticles delivering gene therapies into cells. These nanoparticles must navigate past the plasma membrane and avoid being trapped by organel…
A sea slug composed entirely of muscle, with no rigid skeleton, can reconfigure its anatomy to simplify the control of feeding movements. This ability, shared with other muscular hydrostats like octopus arms and elephant…
While Cyclospora infections have reached record levels in the US this year, experts caution that media coverage has exaggerated the situation as a single massive outbreak. The reality is more complex, with multiple facto…
New research shows that fishing nets are the leading cause of death for common dolphins stranded on Cornwall's coast. The study underscores the impact of fishing gear on marine mammal populations. Conservation efforts ma…
Using 16 million NASA-GEDI satellite estimates, researchers found that tropical forests in the Amazon, Congo Basin, and Southeast Asia respond differently to climate in terms of aboveground biomass. The study, published …
The federal government is increasing funding to combat feral hogs, which have become a growing problem for decades. New research indicates that a recently revived coordinated federal effort could effectively bring the ho…
Fungi form vast underground networks that can be among Earth's oldest living organisms, but their continuous growth, splitting, and recycling make it difficult to define their age. Researchers still lack methods to measu…
Researchers identified a synthetic sugar molecule naturally found in Candida auris cell walls but absent in humans. This molecule could be used to develop a vaccine, generate protective antibodies, and create a rapid dia…
A study in Biology Letters finds that the elaborate suicidal somersault behavior of male Australian redback spiders may be controlled by simple genetic factors, while other aspects of their mating behavior are more genet…
A study in Proceedings of the National Academy of Sciences shows that increasing the diversity of vegetable species, traditional varieties, and wild relatives can improve human nutrition and make agriculture more resilie…
A joint study by Constructor University and Princeton University reveals that the PC645 protein complex in cryptophyte algae adjusts photosynthesis in response to pH changes. This mechanism allows the algae to efficientl…
Researchers placed pigs in high-pressure tanks while outfitted with heated diving suits and diapers to study decompression sickness, commonly known as 'the bends.' The study suggests that maintaining body warmth during a…
Researchers have uncovered how metformin, a widely prescribed diabetes medication, works by altering the gut to absorb and sequester sugar. This newly understood mechanism explains the drug's effectiveness in lowering bl…
Researchers have developed an AI system that learns the biological principles of antibodies to efficiently screen billions of candidates. This approach identifies rare antibody molecules that bind tightly to disease targ…
Researchers analyzing the deepest origins of life found evidence that the first free-living cells may have arisen not once but twice. The findings imply that life shares a single ancient genetic code yet underwent two se…
Researchers extracted keratin from sheep wool and used it as a scaffold to regenerate damaged bone in animal models. The resulting tissue was more organized and structurally similar to natural bone than tissue grown with…
Millions of liters of polluted water flow daily into South African rivers and out to sea. A natural filter is being used to clean the heavily contaminated water, making it safe for watering food gardens. The river's bact…
Researchers used artificial intelligence to design complete genomes for bacteriophages. When synthesized and tested, some of these computer-generated designs yielded functional viruses. This breakthrough raises questions…
A study published in Genome Biology and Evolution examined the DNA of all four Asian elephant subspecies, revealing significant differences in their genetic health. The research shows that some populations are far more g…
A Yale-led study of over 500 North American bird species finds that extreme weather events like heat waves and cold snaps are now major factors limiting where birds can live. The research shows that species ranges and bi…
Tomato plants require precise flower development and fertilization to produce fruit, which is hindered by cold weather. Scientists have identified a genetic switch that could allow tomatoes to fruit even in cold conditio…
Researchers have developed a biotechnological method where microbes use carbon dioxide, hydrogen, and oxygen to produce proteins and vitamin B9 for human consumption. This approach bypasses traditional agriculture and li…
Scientists discovered a new frog species, Adenomera varcena, in the flooded forests of the western Amazon. The species was distinguished from similar-looking frogs by analyzing its call and DNA. This finding highlights t…