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Inhaled Amikacin Combination Improves MAC Culture Conversion With Rare Resistance in ENCORE

Contagion Live · Infectious disease ·

In the phase 3b ENCORE trial, adding amikacin liposome inhalation suspension to azithromycin and ethambutol led to significantly better culture conversion in patients newly diagnosed with MAC lung disease. Resistance emerging during treatment was rare for amikacin (2.2%) and macrolides (1.1%). Kevin

Zoliflodacin Preserves Gonorrhea Cure Rates in Chlamydia Coinfections

Contagion Live · Infectious disease ·

New IDWeek 2026 data indicate that zoliflodacin remains effective for curing gonorrhea in people with concurrent chlamydia. David Altarac, MD, spoke about the therapy and the trial.

Isavuconazole Shows Favorable Liver Safety Signal in Antifungal Analysis

Contagion Live · Infectious disease ·

In a FAERS analysis, isavuconazole had the weakest hepatobiliary adverse-event reporting signal among five azole antifungals, lower than voriconazole and posaconazole. Even so, all five agents showed notable liver-related reporting signals, leading researchers to advise liver function monitoring for

Facewatch launches free tool for retailers to log shoplifting incidents

Talking Retail · Small business ·

Facewatch is testing a new platform called Facewatch Live that lets retailers record incidents, store evidence and analyse crime data at no cost. The service can be used alone or alongside the company’s live facial recognition system, and police will also have free access. Facewatch said the tool is

Co-op Wholesale agrees five-year supply contract covering 35 stores

Talking Retail · Mergers & acquisitions ·

Co-op Wholesale and VST have signed a five-year agreement covering 35 convenience stores in south-west England and along the south coast. The first converted outlet, Loop Convenience in Weymouth, has opened in a former Spar site after a full refit. The stores will carry Co-op products under the Prou

Poll finds strong shopper interest in deposit return scheme

Talking Retail · Small business ·

A YouGov survey found that 71% of shoppers would return drink containers to recover a 20p deposit under the planned deposit return scheme. Most respondents preferred return machines at supermarkets, while only 11% chose convenience stores, and 61% had not heard of the scheme before the poll. Distanc

Independent shops back government plan to ease admin burdens

Talking Retail · Small business ·

The government has accepted 15 proposals from a small business taskforce aimed at reducing administrative work for shop owners. The recommendations cover standardising local licensing applications, simplifying business rates information requests and helping small food businesses meet labelling rules

Bestway expands field team to support independent shops

Talking Retail · Small business ·

Bestway Wholesale has appointed 23 territory sales managers to work directly with independent retailers. The managers will be backed by two regional field sales leaders and a national retail controller. They will help shop owners review ranges, spot category gaps and improve promotions as they deal

Amex Profit Beat Clouded by Higher Costs and Staff Cuts

Sharper Trades · Corporate earnings ·

American Express reported third-quarter revenue of about $20.1 billion, up 9% from a year earlier, though the result slightly missed analyst expectations. Adjusted earnings per share reached $4.68, topping forecasts, while reported EPS was $5.42 after a gain from selling its Global Business Travel G

Harvard Graduate Union Strike Vote Raises Legal Protection Questions

OnLabor · Labor & employment ·

Harvard's managing director of labor and employee relations posted a public message addressed to HGSU-UAW as the union votes on whether to authorize another strike. The message was dated October 2, 2026, and the article considers whether a walkout would be legally protected.

Justices handle a flurry of emergency requests and new cases

SCOTUSblog · Courts & law ·

This weekly roundup covers several developments on the Supreme Court’s interim docket, including a refusal to let the Trump administration enforce a new transgender inmate policy. The justices also received a fresh administration request concerning border-wall construction in Big Bend and agreed to

How Roberts built a majority to broaden presidential removal power

SCOTUSblog · Courts & law ·

The article examines Chief Justice John Roberts’s long campaign to increase presidential authority over federal agencies. It explains how the court’s decision in Trump v. Slaughter let the president remove leaders of nearly all independent agencies, overturning the framework of Humphrey’s Executor.

Texas poster mandate faces a constitutional test at the Supreme Court

SCOTUSblog · Courts & law ·

The Supreme Court is preparing to decide whether to take up a 5th Circuit decision that sustained a Texas law requiring Ten Commandments posters in public school classrooms. The article argues that the appeals court correctly assessed the establishment clause question by looking at historical govern

Nirsevimab Protects High-Risk Young Children in Second RSV Season

MedPage Today · Infectious disease ·

CDC real-world case-control data showed nirsevimab was 75% effective against RSV hospitalization among eligible children ages 8 to 23 months during their second RSV season. Effectiveness was higher when given within 60 days before symptoms and lower when given earlier. The study supports current rec

Hospitals Challenge Upcoming 340B Rebate Overhaul in Court

MedPage Today · Healthcare systems ·

The American Hospital Association, safety-net hospitals, and the Maine Hospital Association sued over changes to the 340B drug discount program set to take effect in January 2027. The new system would require hospitals to pay full drug prices and seek rebates afterward, which hospitals say will cost

Limited Local Neurology and Imaging Access May Slow MS Diagnosis

MedPage Today · Healthcare systems ·

A retrospective study of nearly 8,300 multiple sclerosis patients found that 55% had a diagnostic delay of at least six months and the median delay was three years. Greater distance from neurologists, MS specialists, and MRI facilities was associated with higher odds of delay. Researchers said this

ADHD Medications Show Promise for Menopause-Related Cognitive Complaints

MedPage Today · Mental health ·

A scoping review of three crossover randomized trials found that lisdexamfetamine and atomoxetine improved women's self-reported executive function during menopause, but not objective cognitive test scores. The findings suggest ADHD medications might help menopausal brain fog, though the evidence re

Kidney Donation Tied to Modest Rise in Pregnancy Blood Pressure Risks

MedPage Today · Public health ·

A Canadian matched cohort study found that women who donated a kidney before pregnancy had higher rates of gestational hypertension, preeclampsia, or eclampsia and of small-for-gestational-age births. Most post-donation pregnancies still proceeded without major complications, and severe early outcom

Seven Retail Strategies to Increase Sales and Profit

Small Business Trends · Small business ·

The article recommends retail sales strategies including staff training, CRM-based personalization, store layout optimization, loyalty programs, and data analytics for inventory decisions. It says these tactics can improve customer engagement, repeat purchases, and profitability. The guidance is dir

How Demo Automation Cuts Sales Prep Time and Tailors Pitches

Small Business Trends · Small business ·

The article describes how demo automation software can cut preparation time by using reusable templates, integrating CRM data, and tailoring presentations with audience analytics. It also mentions AI-driven messaging adjustments, automated reminders, and on-demand demos to improve prospect engagemen

Five Building Blocks for Effective Employee Performance Reviews

Small Business Trends · Labor & employment ·

The article outlines five components for an effective performance review document: clear criteria tied to company goals, employee self-assessment, feedback from multiple sources, future objectives, and actionable development guidance. It recommends frequent reviews, such as quarterly or twice yearly

Lyft Adds Fast Phone Recovery Option for Riders

Small Business Trends · Small business ·

Lyft introduced a service that lets riders request a return ride through its Help Center to recover a phone left in a vehicle. The company says most phones are returned the same day, with many back within two hours, and it plans to extend the feature to other misplaced items by winter 2026. The arti

Simulations expose overlooked energy loss in quantum crystal defects

ScienceDaily · Physics ·

University of Chicago researchers developed a computational approach to model how light interacts with spin defects in materials such as silicon carbide. The simulations revealed that internal conversion, an energy-loss process, plays a larger role than previously assumed. Better understanding of th

Light-controlled muscle cells propel a tiny swimming robot

ScienceDaily · Biology & genetics ·

MIT engineers created a thin, gel-based swimmer whose fins are coated with light-sensitive muscle cells. Flashing light on either fin makes it flap, allowing researchers to steer the device through an underwater maze. The robot moved about four body lengths per minute and represents a step toward sm

Brain-mapping stimulation therapy shows strong PTSD results in early trial

ScienceDaily · Neuroscience ·

A personalized PTSD therapy that pairs brain-activity mapping with magnetic stimulation has received FDA clearance. In an early trial, participants reportedly had a 52% drop in symptoms and 68% reached remission, though full results are not yet public. The approach is being developed as an alternati

Corroded titanium particles may explain implant-related jawbone damage

ScienceDaily · Biology & genetics ·

A Rutgers-led study found that bacteria can degrade titanium dental implants and release tiny metal particles into surrounding tissue. These particles activate a calcium channel in macrophages, keeping immune cells in an inflammatory state that damages jawbone. Blocking that channel prevented the co

Seismic survey detects magma recharge beneath Japanese supervolcano

ScienceDaily · Physics ·

Researchers used seismic imaging beneath Japan’s Kikai caldera to find a large magma body that has been building up since a huge eruption about 7,300 years ago. The work offers insight into how supervolcanoes such as Yellowstone and Toba recharge after major blasts. It may help scientists identify s

Researchers link Europe’s severe summer heat to tens of thousands of deaths

Grist · Extreme weather ·

A new analysis estimates that Europe’s record-hot summer caused more than 50,000 excess deaths in cities, making it the deadliest such season on record. Researchers modeled conditions across 854 urban areas and linked about two-thirds of those deaths to human-caused warming, far exceeding the tolls

Event to examine trust and accurate information during extreme weather

Grist · Extreme weather ·

Grist and Climate Central will host a virtual discussion on October 28 about how misinformation spreads during extreme weather and how to communicate more reliably. Meteorologists, journalists, and researchers will take questions and share guidance for conversations before, during, and after such di

Ashton urges England to chase points without losing discipline

BBC Sport · Football (NFL) ·

Matty Ashton says England must pursue a big win over France in their Rugby League World Cup group match without losing their discipline. England need to improve their points difference after losing to Tonga and seeing Samoa beat France heavily.